| Min | Event | Player | Team | Detail | Ref call |
|---|---|---|---|---|---|
| 20' | Yellow | Edmond Tapsoba | Bayer Leverkusen | Yellow Card | — |
| 20' | Yellow | Gianluca Mancini | AS Roma | Yellow Card | — |
| 21' | Yellow | Lorenzo Pellegrini | AS Roma | Yellow Card | — |
| 27' | Yellow | Leandro Paredes | AS Roma | Yellow Card | — |
| 29' | Yellow | Nicola Zalewski | AS Roma | Yellow Card | — |
| 41' | Yellow | Jonathan Tah | Bayer Leverkusen | Yellow Card | — |
| 43' | Penalty | L. Paredes | AS Roma | Penalty | — |
| 64' | Penalty | Bryan Cristante | AS Roma | Penalty confirmed | — |
| 66' | Penalty | L. Paredes | AS Roma | Penalty | — |
| 82' | Goal | G. Mancini | Bayer Leverkusen | Own Goal | — |
| 89' | Yellow | Florian Wirtz | Bayer Leverkusen | Yellow Card | — |
| 90' | Goal | J. Stanišić | Bayer Leverkusen | Normal Goal | — |